Best Edibles for Depression

With a vast array of cannabis edibles on the market, patients have more options to explore than ever. Each edible offers a unique combination that delivers specific effects, from gummies to baked goods. 

For new cannabis consumers, navigating across such a list may be confusing or even overwhelming. Identifying the right edible is crucial for many patients living with different ailments, including those seeking relief from depression. 

Choosing the best edibles for depression may significantly impact one's quality of life by providing much-needed relief from symptoms. This guide explores essential questions about edibles and depression and includes a list of the top gummies for the condition.

Can Weed Help with Depression?

Current research supports that cannabis could play a role in alleviating symptoms of depression. CBD, in particular, has shown potential as a therapeutic agent for anxiety and depression by helping to regulate certain receptors that are linked to depression. It could do so by interacting with receptors in the brain and body that regulate mood.¹

Participants in a study used the Strainprint app to track their symptoms after using cannabis. 89.3% of tracked sessions resulted in less depressive symptoms after cannabis consumption. Notably, low-THC and high-CBD strains may provide more significant relief than high-THC strains. These studies add more evidence to the theory that cannabis may improve a depressed mood.²

With high-THC cannabis, though, patients may instead risk exacerbating their symptoms. Although cannabis may have a range of effects in high THC concentrations and edible forms, the substance may be quite relaxing and even sedating. For patients experiencing depression, symptoms may already include excessive sleep. A high THC content, especially with chronic use, may not reduce symptoms of depression.³  

These varied results highlight why it's so important to find the right balance of cannabinoids for each individual.

Patient-reported outcomes further support the potential benefits of cannabis for depression. A survey found that 53% of respondents felt better after using CBD, with 88% preferring CBD over prescription medications.⁴ In other research, CBD may be a potential therapeutic strategy for depression.^5,6

Additionally, CBG-predominant cannabis products may improve depression symptoms. 80% of users claimed superior efficacy compared to conventional medicines.⁷ 

These findings suggest CBD and CBG could offer patients relief from depression and anxiety. This may be particularly helpful for those who are resistant to traditional antidepressant treatments.

Overall, while anecdotal evidence and preliminary studies are promising, more comprehensive clinical trials are needed to demonstrate cannabis's role in managing depression. Patients considering cannabis for depression should consult with healthcare professionals to determine the most suitable approach for their needs.

Best Types of Edibles for Depression?

Cannabis edibles are discreet, easy to consume, and available in various flavors. Many patients tend to enjoy the longer-lasting effects they provide.

Several edible options are available to consumers, including baked goods, chocolates, and beverages. Baked goods like brownies and cookies offer a classic and comforting way to consume cannabis. However, gummies are often the most popular choice. The best gummies for depression are usually favored for their effects, convenience, and precise dosing. 

Cannabis and dark chocolate might provide synergistic effects, enhancing the experience. Research suggests that chocolate consumption, especially dark chocolate, may offer mood-enhancing effects.⁸

While most edibles take effect anywhere from 30 minutes to 2 hours before the full effects are felt, consumers may also have the option to purchase fast-acting edibles, which could take effect in 15 to 30 minutes. These may be better for patients seeking quicker relief from their depressive symptoms. 

Try to avoid edibles with artificial additives and high sugar content. These ingredients may have adverse effects on mood and overall health.⁹ Opting for high-quality, natural ingredients may enhance the therapeutic benefits for patients. This standard of quality may be best achieved by making your own edibles. 

Homemade weed gummies can be customized to fit dietary needs and flavor preferences. 

Ultimately, the best edibles for depression are those that align with individual preferences and needs.

How to Choose Edibles for Depression

When selecting the best edibles for depression, there are several factors to consider. Patients should start by assessing their desired effects and personal preferences.

Verify Product Quality with a COA

The first step in choosing edibles is to look for products with a certificate of analysis (COA). A COA provides detailed information about the edible's cannabinoid and terpene content. It's also essential for verifying the product's potency and safety. Check the product packaging and labels for a COA QR code. This should link to lab results, ensuring you get quality products.

Consider Dosage and Potency

Consider the dosage when choosing the best edibles for depression. Most legal edibles are available in standard doses, typically 5mg or 10mg of THC per serving. Start with a low dose, anywhere from 1-5mg, especially for those new to cannabis. 

Starting low and going slow is an approach that allows patients to gauge tolerance levels and adjust as needed. It's always better to take not enough than too much. Once an edible is consumed, the onset time can range from 30 minutes to an hour. The duration of effects may last two to eight hours.¹⁰

Likewise, understand whether you have a CBD or THC edible. The difference can drastically determine what symptoms the product helps with.

Ensure the edibles are scored (have a line or mark) for the best results. The label should provide instructions on dosing for that specific edible.

Explore Homemade Edibles

Making edibles at home can be a cost-effective option, but it requires knowing the THC percentage of your ingredients. Otherwise, one can't estimate dosing. Likewise, homemade edibles may not be as accurate as regulated products.

Choose the Right Cannabinoid Profile

Patients should consider using low-THC, high-CBD edibles and those rich in CBG. These cannabinoids are known for their potential antidepressant effects and may offer a more balanced experience. These options may be particularly beneficial for those sensitive to THC's intoxicating effects.

Ultimately, choosing the right edibles involves understanding personal needs and preferences. Patients should explore and document different products and approaches to find what works best for them. Consulting with healthcare professionals can also provide valuable guidance in this journey.

The 5 Best Edibles for Depression

Certain edibles stand out for their effectiveness and patient satisfaction. Below are five of the best edibles for depression, according to consumers, featuring various forms and cannabinoid profiles.

1. Wyld CBD Pear Gummies

Wyld CBD Pear Gummies are a favorite among patients for their balance of flavor and therapeutic effects. These gummies contain a blend of CBD and CBG, which may relieve symptoms of depression and anxiety without THC's intoxicating effects. Patients report feeling relaxed and calm after consuming these gummies for depression. Their natural pear flavor makes them a tasty and appealing option.

2. Smokiez CBD Gummies

Smokiez CBD Gummies offer a high-quality alternative for those seeking relief from depression. These gummies come in various flavors, providing a delightful taste while delivering the benefits of CBD. Patients often note a reduction in anxiety and an improvement in mood. Many users appreciate their consistent potency and effectiveness.

3. PLUS Tart Cherry Gummies

PLUS Tart Cherry Gummies are well-regarded for their delicious flavor and mood-enhancing properties. Infused with mg THC, 20mg CBD, and 5mg of CBG, these gummies may provide an ideal experience to relieve anxiety and depression symptoms. They are a popular choice for daily use.

4. Kiva Confections CBD 5:1 Dark Chocolate

Kiva Confections CBD 5:1 Dark Chocolate combines CBD's mood-enhancing effects with dark chocolate's natural benefits. The bar has a rich chocolate flavor with hints of vanilla and a silky smooth texture. Some patients find it a soothing experience that helps manage depression symptoms. The 5:1 CBD:THC ratio ensures a gentler effect, ideal for those seeking relaxation without intoxication.

5. Kanha CBD Gummies

Patients praise Kanha's CBD gummies for their potent effects and flavor variety. Crafted with care, these gummies offer consistent CBD doses for reliable symptom relief. Patients report feeling more balanced and at ease. The vegan-friendly recipe and quality ingredients further enhance their appeal. Alternatively, some patients may prefer to make edibles at home. In that case, many recipes for weed cupcakes, brownies, and other edibles are available online.

References

1. García-Gutiérrez MS, Navarrete F, Gasparyan A, Austrich-Olivares A, Sala F, Manzanares J. Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders. Biomolecules. 2020; 10(11):1575. https://doi.org/10.3390/biom10111575 ↩︎
2. Feingold D, Weinstein A. Cannabis and Depression. Cannabinoids and Neuropsychiatric Disorders. 2020;1264:67-80. doi:https://doi.org/10.1007/978-3-030-57369-0_5 ↩︎
3. Langlois C, Potvin S, Khullar A, Tourjman SV. Down and High: Reflections Regarding Depression and Cannabis. Front Psychiatry. 2021;12:625158. Published 2021 May 14. doi:10.3389/fpsyt.2021.625158 ↩︎
4. Wieckiewicz G, Stokłosa I, Stokłosa M, Gorczyca P, Pudlo R. Cannabidiol (CBD) in the Self-Treatment of Depression-Exploratory Study and a New Phenomenon of Concern for Psychiatrists. Front Psychiatry. 2022;13:837946. Published 2022 Mar 22. doi:10.3389/fpsyt.2022.837946 ↩︎
5. Pinto JV, Saraf G, Frysch C, et al. Cannabidiol as a Treatment for Mood Disorders: A Systematic Review. Can J Psychiatry. 2020;65(4):213-227. doi:10.1177/0706743719895195 ↩︎
6. Pinto JV, Crippa JAS, Ceresér KM, et al. Cannabidiol as an Adjunctive Treatment for Acute Bipolar Depression: A Pilot Study: Le cannabidiol comme traitement d’appoint de la dépression bipolaire aiguë : une étude pilote. The Canadian Journal of Psychiatry. 2024;69(4):242-251. doi:10.1177/07067437231209650 ↩︎
7. Russo EB, Cuttler C, Cooper ZD, Stueber A, Whiteley VL, Sexton M. Survey of Patients Employing Cannabigerol-Predominant Cannabis Preparations: Perceived Medical Effects, Adverse Events, and Withdrawal Symptoms. Cannabis and Cannabinoid Research. 2021;7(5). doi:https://doi.org/10.1089/can.2021.0058 ↩︎
8. Jackson SE, Smith L, Firth J, et al. Is there a relationship between chocolate consumption and symptoms of depression? A cross-sectional survey of 13,626 US adults. Depress Anxiety. 2019;36(10):987-995. doi:10.1002/da.22950 ↩︎
9. Zhang L, Sun H, Liu Z, Yang J, Liu Y. Association between dietary sugar intake and depression in US adults: a cross-sectional study using data from the National Health and Nutrition Examination Survey 2011–2018. BMC Psychiatry. 2024;24(1). doi:https://doi.org/10.1186/s12888-024-05531-7 ↩︎
10. MacCallum CA, Russo EB. Practical considerations in medical cannabis administration and dosing. European Journal of Internal Medicine. 2018;49(49):12-19. doi:https://doi.org/10.1016/j.ejim.2018.01.004 ↩︎

The information in this article and any included images or charts are for educational purposes only. This information is neither a substitute for, nor does it replace, professional legal advice or medical advice, diagnosis, or treatment. If you have any concerns or questions about laws, regulations, or your health, you should always consult with an attorney, physician or other licensed professional.