Key Takeaways
- Research suggests THC and CBD may reduce ADHD symptoms by improving focus and reducing hyperactivity.
- A balance of THC and CBD, along with other cannabinoids like CBC and CBG, may enhance dopamine regulation.
- Strains like Green Crack, Cannatonic, and GMO Cookies have been shown to help with ADHD.
Attention deficit hyperactivity disorder (ADHD) can significantly impact concentration and decision-making, complicating the search for effective treatments. Research into cannabis for ADHD, mainly focusing on cannabinoids like THC and CBD, shows the potential to reduce some symptoms.
However, for new patients, finding suitable strains and determining the best cannabinoid concentrations can be challenging. This process is vital to maximize health benefits and minimize potential side effects.
It’s important to explore how different cannabinoids might help manage ADHD symptoms. Understanding the research behind it may help you choose the right strains for effective relief.
Which Cannabinoids Help Most With ADHD?
Traditional ADHD treatments often involve stimulants like Adderall or non-stimulant medications, each with potential side effects and varying effectiveness.
As an alternative, research into cannabinoids offers new hope by directly targeting the endocannabinoid system. This approach is believed to correct the dopamine dysfunction that underlies many of ADHD’s clinical symptoms.
Research shows that specific cannabinoids like THC, CBD, CBC, and CBG may help people with ADHD by affecting brain chemistry related to dopamine and serotonin pathways.
For instance, increasing anandamide (AEA) levels, which are linked to dopamine release, has shown promise in managing ADHD symptoms. Synthetic stimulants and amphetamines work by increasing levels exogenously or outside of the natural system. Synthetic and natural FAAH inhibitors prevent the breakdown of AEA in the nervous system, increasing dopamine production. Research shows that specific cannabinoids like THC, CBN, CBC, and CBG activate AEA receptors, increasing dopamine concentrations, while CBD releases serotonin.1
Clinical studies show that using medicinal cannabis for ADHD may improve the quality of life, sleep, and anxiety. They also reduce reliance on traditional ADHD medications like lisdexamfetamine, methylphenidate, and dexamfetamine, with relatively few adverse effects. However, this study did not assess whether adverse events, such as concentration impairment, were directly related to cannabis or underlying symptoms of ADHD.2
A small case study involving three patients found that patients using cannabis with a CBD ratio of 20:1 reported benefits in managing ADHD symptoms. However, patient preferences varied, with two preferring high-THC strains and one using a product with a low CBD-to-THC ratio. Another patient’s CBD 20:1 product was found to contain high THC and no CBD, raising concerns about product labeling accuracy.3
Many individuals with ADHD report improvements in symptoms such as inattention and hyperactivity-impulsivity when using cannabis. Specifically among certain online forms, a study reported that 74% of users noted benefits for inattentive symptoms, 16% for hyperactive-impulsive symptoms, and 10% for both.4
Additionally, self-reported effects from cannabis users with ADHD indicate that cannabis helps manage various symptoms. These include hyperactivity, impulsivity, and medication side effects like irritability and anxiety. The frequency of use was a significant factor in improving symptom severity and executive dysfunction.5
Cannabis for ADHD: The Best Cannabinoid Ratios and Combos
Cannabinoids may offer a promising alternative to traditional ADHD treatments by targeting the endocannabinoid system (ECS). The ECS plays a role in regulating mood, attention, and other cognitive functions. Knowing the specific concentrations and ratios of cannabinoids that provide the most benefit may help patients effectively use cannabis for ADHD.
High CBD ratios, such as 20:1 CBD to THC, have been reported to help manage symptoms of ADHD effectively.3 This high CBD ratio is often noted for its calming effects, which may help reduce anxiety and improve focus without causing the intoxicating effects commonly associated with high THC levels.
While high-THC strains are reported to help some individuals with symptoms of ADHD, caution is advised due to potential impairment. Products high in THC have been reported to provide symptom relief, but accurate labeling and proper dosing are crucial to avoid unexpected effects.
Cannabichromene (CBC) and cannabigerol (CBG) activate AEA receptors and increase dopamine levels, which may help reduce ADHD symptoms.
A balance of cannabinoids, including CBC and CBG, may enhance dopamine regulation. These cannabinoids may work together to manage symptoms by interacting with the brain’s chemistry. The modulation of the endocannabinoid system through these cannabinoids may help reduce common ADHD symptoms like inattention, hyperactivity, and impulsivity.1
When considering cannabinoid treatment for ADHD, start with low doses and gradually increase as needed.6 Consult with a healthcare provider experienced in cannabis therapy to determine the most effective and safe dosages.
How to Choose Strains for ADHD Based on Cannabinoid Content
Choosing the right cannabis strain for ADHD can be challenging, especially given the wide variety of options available. However, by focusing on specific factors such as cannabinoid content and terpene profiles, consumers looking to use cannabis for ADHD can find the most effective strains for managing their symptoms.
Cannabinoid Content
Cannabinoid ratios are important for effective ADHD management. High-CBD strains are often recommended for their calming effects without causing overintoxication. However, some ADHD patients may benefit from strains with higher THC content, particularly if they find it helps with focus and reducing hyperactivity.
Terpene Profiles
Terpenes, some of the aromatic compounds in cannabis, may also play a significant role in the effects of different strains. For ADHD, terpenes like limonene (uplifting mood and improving focusing), pinene (improving focus), and linalool (calming) may be helpful, according to some research.7,8 Look for strains with terpene profiles that match your desired effects.
Secondary Cannabinoids
In addition to THC and CBD, minor cannabinoids like cannabichromene (CBC) and cannabigerol (CBG) are important. These cannabinoids may enhance dopamine regulation and improve overall symptom management in ADHD patients.1
Certificate of Analysis
A certificate of analysis (COA) provides information about the product’s cannabinoid and terpene content. Checking the COA ensures the strain has the desired profile and helps avoid mislabeled products. Look for COAs from reputable third-party labs for the most accurate results.
Consult a Healthcare Provider
Working with a knowledgeable healthcare provider can help patients find the right choice in strains that meet their needs and symptoms. They can provide guidance on starting doses, delivery methods, and adjusting the cannabinoid ratios based on the patient’s response.
Experiment with Different Strains
It may take some trial and error to find the most effective strain to manage ADHD symptoms. Starting with small amounts and gradually increasing the dosage can help users find the optimal strain without the overwhelming side effects, such as anxiety, paranoia, and dizziness. Keeping a journal of strains tried, their effects, and any side effects can help track progress and identify the best options.
The 5 Best Strains for ADHD Based on Cannabinoid Content
The right cannabis strains may ease symptoms of ADHD, putting users on more stable ground and able to tackle their day. Here are just a few of the best strains for ADHD self-reported by other patients.
Green Crack
Green Crack is a high-THC strain known for its stimulating effects. This strain might provide a rush of euphoria and increased focus, potentially benefiting those needing a mental boost. Its tropical and fruity aroma adds to its appeal.
Mimosa
Mimosa may offer a balanced and energetic high, with 20% THC and 1% CBG. The strain’s citrus, earthy, and fruity aroma may make it a refreshing choice for managing ADHD symptoms. Mimosa's cannabinoid and terpene profile is said to help promote a clear-headed experience without overwhelming intoxication.
GMO Cookies combine high THC levels with a touch of CBG and is often said to provide relaxation, euphoria, and stress relief. This strain’s sweet and savory aroma enhances its appeal.
White CBG
White CBG is a strain that features approximately 10% CBG and only trace amounts of THC. This potentially makes it an excellent choice for enhancing concentration and reducing anxiety without the intoxicating effects of THC. White CBG is reported to be particularly helpful for those who need to stay focused and alert without feeling overly stimulated.
Cannatonic
Cannatonic is known for its balanced cannabinoid ratio, with 9% CBD and 4% THC. This combination is said to offer a calming effect without the overwhelming high typically associated with higher THC strains. Cannatonic may help users achieve a mind and body buzz, promoting relaxation and focus. Its balanced profile makes it a versatile option for managing various ADHD symptoms.
References
- Dawson DA, Persad CP. Targeting the Endocannabinoid System in the Treatment of ADHD. Genetics & Molecular Medicine. 2021;3(1). doi:https://doi.org/10.33425/2689-1077.1006 ↩︎
- Ittiphakorn P, Erridge S, Holvey C, Coomber R, Rucker JJ, Sodergren MH. UK Medical Cannabis Registry: An analysis of clinical outcomes of medicinal cannabis therapy for attention‐deficit/hyperactivity disorder. Neuropsychopharmacology Reports. 2023;43(4):596-606. doi:https://doi.org/10.1002/npr2.12400 ↩︎
- Mansell H, Quinn D, Kelly LE, Alcorn J. Cannabis for the Treatment of Attention Deficit Hyperactivity Disorder: A Report of 3 Cases [published correction appears in Med Cannabis Cannabinoids. 2022 Sep 30;5(1):128]. Med Cannabis Cannabinoids. 2022;5(1):1-6. Published 2022 Jan 13. doi:10.1159/000521370 ↩︎
- Mitchell JT, Sweitzer MM, Tunno AM, Kollins SH, McClernon FJ. "I Use Weed for My ADHD": A Qualitative Analysis of Online Forum Discussions on Cannabis Use and ADHD. PLoS One. 2016;11(5):e0156614. Published 2016 May 26. doi:10.1371/journal.pone.0156614 ↩︎
- Stueber A, Cuttler C. Self-Reported Effects of Cannabis on ADHD Symptoms, ADHD Medication Side Effects, and ADHD-Related Executive Dysfunction. Journal of Attention Disorders. 2021;26(6):108705472110509. doi:https://doi.org/10.1177/10870547211050949 ↩︎
- MacCallum CA, Russo EB. Practical considerations in medical cannabis administration and dosing. European Journal of Internal Medicine. 2018;49(49):12-19. doi:https://doi.org/10.1016/j.ejim.2018.01.004 ↩︎
- Lewis MA, Russo EB, Smith KM. Pharmacological Foundations of Cannabis Chemovars. Planta Medica. 2017;84(04):225-233. doi:10.1055/s-0043-122240 ↩︎
- Weston-Green K, Clunas H, Jimenez Naranjo C. A Review of the Potential Use of Pinene and Linalool as Terpene-Based Medicines for Brain Health: Discovering Novel Therapeutics in the Flavours and Fragrances of Cannabis. Frontiers in Psychiatry. 2021;12. doi:https://doi.org/10.3389/fpsyt.2021.583211 ↩︎
The information in this article and any included images or charts are for educational purposes only. This information is neither a substitute for, nor does it replace, professional legal advice or medical advice, diagnosis, or treatment. If you have any concerns or questions about laws, regulations, or your health, you should always consult with an attorney, physician or other licensed professional.
